Selected Publications
Ruscitto A, Peng C, Tosa I, Wang Z, Zhou G, Safina I, Wei R, Morel M, Koch A, Forman M, Reeve, G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang T, Yao H, Embree MC. Cell Stem Cell. Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. (in press)
Tosa I, Ruscitto A, Wang Z, Chen KZ, Ono M, Embree MC. Bulk RNA-seq analyses of mandibular condylar cartilage in a post-traumatic TMJ osteoarthritis rabbit model. Orthod Craniofac Res. 2023 Mar 8;. doi: 10.1111/ocr.12649. [Epub ahead of print] PubMed PMID: 36891610; NIHMSID:NIHMS1892718.
Safina I, Embree MC. Biomaterials for recruiting and activating endogenous stem cells in situ tissue regeneration. Acta Biomater. 2022 Apr 15;143:26-38. doi: 10.1016/j.actbio.2022.03.014. Epub 2022 Mar 12. Review. PubMed PMID: 35292413; PubMed Central PMCID: PMC9035107.
Ruscitto A, Morel MM, Shawber CJ, Reeve G, Lecholop MK, Bonthius D, Yao H, Embree MC. Evidence of vasculature and chondrocyte to osteoblast transdifferentiation in craniofacial synovial joints: Implications for osteoarthritis diagnosis and therapy. FASEB J. 2020 Mar;34(3):4445-4461. doi: 10.1096/fj.201902287R. Epub 2020 Feb 6. PubMed PMID: 32030828; PubMed Central PMCID: PMC7380713.
Ruscitto A, Scarpa V, Morel M, Pylawka S, Embree MC. Notch Regulates Fibrocartilage Stem Cell Fate and Is Upregulated in Inflammatory TMJ Arthritis. J Dent Res. 2020 Sep;99(10):1174-1181. doi: 10.1177/0022034520924656.PMID: 32442041; PubMed Central PMCID: PMC7443994.
Morel M, Ruscitto A, Pylawka S, Reeve G, Embree MC. Extracellular matrix turnover and inflammation in chemically-induced TMJ arthritis mouse models. PLoS One. 2019;14(10):e0223244. doi: 10.1371/journal.pone.0223244. eCollection 2019. PubMed PMID: 31603905; PubMed Central PMCID: PMC6788689.
Nathan J, Ruscitto A, Pylawka S, Sohraby A, Shawber CJ, Embree MC. Fibrocartilage Stem Cells Engraft and Self-Organize into Vascularized Bone. J Dent Res. 2018 Mar;97(3):329-337. doi: 10.1177/0022034517735094. Epub 2017 Oct 11. PubMed PMID: 29020504; PubMed Central PMCID: PMC5833184.
*Embree MC, Chen M, Pylawka S, Kong D, Iwaoka GM, Kalajzic I, Yao H, Shi C, Sun D, Sheu TJ, Koslovsky DA, Koch A, Mao JJ. Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury. Nat Commun. 2016 Oct 10;7:13073. doi: 10.1038/ncomms13073. PubMed PMID: 27721375; PubMed Central PMCID: PMC5062541.
*Embree MC, Iwaoka GM, Kong D, Martin BN, Patel RK, Lee AH, Nathan JM, Eisig SB, Safarov A, Koslovsky DA, Koch A, Romanov A, Mao JJ.Soft tissue ossification and condylar cartilage degeneration following TMJ disc perforation in a rabbit pilot study. Osteoarthritis Cartilage. 2015 Apr;23(4):629-39. doi: 10.1016/j.joca.2014.12.015. Epub 2015 Jan 5. PubMed PMID: 25573797; PubMed Central PMCID: PMC4368469.
Complete Listing on PubMed Here →